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Paget’s disease of bone is a chronic disorder characterized by abnormal bone remodeling. The pelvic brim sign arises due to excessive bone resorption due to increased osteoclastic activity in the early stages of the disease leads to localized bone loss, as well as excessive bone formation during the later stages of the diseases.
Paget's disease of bone is the second most common metabolic bone disorder, after osteoporosis. [37] The overall prevalence and severity of Paget's disease are decreasing; the cause for these changes is unclear. [38] Paget's disease is rare in people less than 55 years of age, [7] and the prevalence increases with age. [38]
Paget's disease may refer to several conditions described by Sir James Paget, surgeon and pathologist: Paget's disease of bone (most common use of the term "Paget's disease") Paget's disease of the breast; Paget–Schroetter disease; Paget's abscess; Extramammary Paget's disease (EMPD)
Osteoporosis circumscripta cranii refers to a highly circumscribed (focal) lytic lesion of the skull bone as seen on X-ray in patients with Paget's disease of bones. [1] This focal lesion can be fairly large. This finding is highly specific for Paget's disease of bones.
There are many bone disorders such as osteoporosis, Paget's disease, hypothyroidism. [2] Although there are many forms of bone disorders, they all have one thing in common; abnormalities of specific organs involved, deficiency in vitamin D or low Calcium in diet, which results in poor bone mineralization .
Paget disease of bone. From Wikipedia, the free encyclopedia. Redirect page. Jump to navigation Jump to search. Redirect to: Paget's disease of bone;
Platybasia is a spinal disease of a malformed relationship between the occipital bone and cervical spine.. It may be caused by Paget's disease.Platybasia is also a feature of Gorlin-Goltz syndrome, commonly known as basal cell nevus syndrome.
Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Paget's disease of bone. PubMed provides review articles from the past five years (limit to free review articles)