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An inotrope [help 1] or inotropic is a drug or any substance that alters the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction.
Cardiotonic agents, also known as cardiac inotropes or stimulants, have a positive impact on the myocardium (muscular layer of the heart) by enhancing its contractility. . Unlike general inotropes, these agents exhibit a higher level of specificity as they selectively target the myocar
Lusitropy or lucitropy is the rate of myocardial relaxation. The increase in cytosolic calcium of cardiomyocytes via increased uptake leads to increased myocardial contractility (positive inotropic effect), but the myocardial relaxation, or lusitropy, decreases.
The antagonism of β 1 inotropic and chronotropic effects decreases the amount of work the heart must perform. It is also thought that catecholamines and other sympathomimetics have an effect on cardiac remodeling, and blocking their activity can slow the deterioration of cardiac function.
Super Bowl 58: $12,128 (Allegiant Stadium, Las Vegas — San Francisco 49ers vs. Kansas City Chiefs). Super Bowl 57: $8,907 (State Farm Stadium, Glendale, ...
Flu A vs. flu B treatment. Treatment for flu A and flu B is the same. “The antivirals that we have—Tamiflu and the like—work well against both A and B,” Dr. Schaffner says.
As the Trump Administration has pursued its goal of reducing government spending, it seems to be taking the same approach as big cats do when pursuing prey: move fast and take down the most ...
In 1897 Engelmann introduced four Greek terms to describe key physiological properties of the heart: inotropy, [4] the ability to contract; chronotropy, the ability to initiate an electrical impulse; dromotropy, the ability to conduct an electrical impulse; and bathmotropy, the ability to respond to direct mechanical stimulation.