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Acquired pure red cell aplasia. Myeloproliferative disorders. Polycythemia vera. Essential thrombocytosis. Myelofibrosis. Metabolic disorders. Amyloidoses. Amyloid light chain (AL) amyloidosis. Environmentally-induced diseases.
Hematopoietic stem cell transplantation. Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells. [1][2][3][4][5][6] HSCT may be ...
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2][3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.
A stem cell transplant – also known as a bone marrow transplant – is a procedure that replaces damaged blood cells with healthy ones - used to treat certain types of cancer and other diseases.
Hematopoietic stem cells (HSCs) are the stem cells [1] that give rise to other blood cells.This process is called haematopoiesis. [2] In vertebrates, the first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within the (midgestational) aorta-gonad-mesonephros region, through a process known as endothelial-to-hematopoietic transition.
Cord blood is being used to get stem cells with which to test in people with type 1 diabetes mellitus. [36] The stem cells from umbilical cord blood are also being used in the treatment of a number of blood diseases including blood cancers. [37] Cord blood is also being studied as a substitute for normal blood transfusions in the developing world.
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