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  2. Glucose-6-phosphate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, it is usually is short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD-deficient ...

  3. Glucose-6-phosphate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is a cytosolic enzyme that catalyzes the chemical reaction. D -glucose 6-phosphate + NADP + + H2O ⇌ 6-phospho- D -glucono-1,5-lactone + NADPH + H +. This enzyme participates in the pentose phosphate pathway (see image), a metabolic pathway that supplies reducing energy to cells ...

  4. 6-phosphogluconate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/6-phosphogluconate_de...

    6PGD deficiency is a recessive hereditary disorder located on the P arm of chromosome 1. It is an autosomal disease, not associated with the sex chromosomes and can affect both sexes. The lack of synthesis of a specific protein on chromosome 1 has reduced a subject suffering from 6PGD deficiency from producing adequate amounts of the 6 ...

  5. Dapsone - Wikipedia

    en.wikipedia.org/wiki/Dapsone

    Dapsone. Dapsone, also known as 4,4'-sulfonyldianiline (SDA) or diaminodiphenyl sulfone (DDS), [2] is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. [3] It is a second-line medication for the treatment and prevention of pneumocystis pneumonia and for the prevention of toxoplasmosis in ...

  6. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic. Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing. However, these classifications are based on laboratory behavior.

  7. Primaquine - Wikipedia

    en.wikipedia.org/wiki/Primaquine

    Primaquine should not be administered to anyone with G6PD deficiency because a severe reaction can occur, resulting in hemolytic anemia. [4] However, the WHO has recommended that a single dose of primaquine (0.25 mg/kg) is safe to give even in individuals with G6PD deficiency, for the purpose of preventing transmission of P. falciparum malaria ...

  8. G6pd deficiency - Wikipedia

    en.wikipedia.org/?title=G6pd_deficiency&redirect=no

    This page was last edited on 19 July 2007, at 05:14 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may ...

  9. Human genetic resistance to malaria - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_resistance...

    G6PD deficiency is the second most common enzyme deficiency in humans (after ALDH2 deficiency), estimated to affect some 400 million people. [40] There are many mutations at this locus, two of which attain frequencies of 20% or greater in African and Mediterranean populations; these are termed the A- and Med mutations. [41]