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Gas gangreneX (also known as clostridial myonecrosis [1]) is a bacterial infection that produces tissue gas in gangrene. This deadly form of gangrene usually is caused by Clostridium perfringens bacteria. About 1,000 cases of gas gangrene are reported yearly in the United States. [2] Myonecrosis is a condition of necrotic damage, specific to ...
Gas gangrene is a bacterial infection that produces gas within tissues. It can be caused by Clostridium , most commonly alpha toxin -producing C. perfringens , or various nonclostridial species. [ 11 ] [ 21 ] Infection spreads rapidly as the gases produced by the bacteria expand and infiltrate healthy tissue in the vicinity.
Gangrene of the skin: ... Dermatitis gangrenosa is a cutaneous condition caused by infection by Clostridium resulting in a necrosis and sloughing of the skin. [1]: ...
Clostridium septicum is a resident bacterium of the human microflora, however it can be found in almost any anoxic habitat in which exists organic compounds. [4] Under unfavorable conditions, C. septicum forms endospores allowing it to survive under harsh conditions such as extreme temperature, dry land, and nutrient-deficient habitats.
This is a subtype of Type I infections affecting the groin and perianal areas. [10] Clostridia account for 10% of overall type I infections and typically cause a specific kind of necrotizing fasciitis known as gas gangrene or myonecrosis. Type II infection: This infection accounts for 20 to 30% of cases, mainly involving the extremities.
Burow’s solution. Burow's solution is an aqueous solution of aluminium triacetate.It is available in the U.S.A. as an over-the-counter drug for topical administration, with under the brand name Domeboro (Moberg Pharma) [1] The preparation has astringent and antibacterial properties and may be used to treat a number of skin conditions, including insect bites and stings, rashes caused by ...
Tolnaftate is included in many products for fungal skin infections such as athlete's foot, jock itch and ringworm. Del Campo says it's best, however, to opt for a preparation designed for nails.
This toxin has been shown to be the key virulence factor in infection with C. perfringens; the bacterium is unable to cause disease without this toxin. [1] Further, vaccination against the alpha toxin toxoid protects mice against C. perfringens gas gangrene. [2]