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University Medical Center, the teaching hospital of Texas Tech University Health Sciences Center in Lubbock. The Texas Tech University Health Sciences Center (TTUHSC) is a public medical school based in Lubbock, Texas, with additional campuses in Abilene, Amarillo, Dallas, and the Permian Basin. TTUHSC serves more than 100 counties in the ...
The School of Medicine (SOM) located in Lubbock, Texas was established as the Texas Tech University School of Medicine in 1969 by the 61st Texas Legislature, and the SOM first graduated Doctors of Medicine in 1974. [3] [4] The SOM has grown into the Texas Tech University Health Sciences Center (TTUHSC), and the SOM is now just one school within ...
Shelterin (also called telosome) is a protein complex known to protect telomeres in many eukaryotes from DNA repair mechanisms, as well as to regulate telomerase activity. In mammals and other vertebrates, telomeric DNA consists of repeating double-stranded 5'-TTAGGG-3' (G-strand) sequences (2-15 kilobases in humans) along with the 3'-AATCCC-5' (C-strand) complement, ending with a 50-400 ...
When the cell does this due to telomere-shortening, the ends of different chromosomes can be attached to each other. This solves the problem of lacking telomeres, but during cell division anaphase, the fused chromosomes are randomly ripped apart, causing many mutations and chromosomal abnormalities. As this process continues, the cell's genome ...
In general, TERRA has been shown to be most abundant in cells with long telomeres, [2] [3] while cells with short telomeres express comparatively lower levels of transcript expression. There is also evidence that overexpression of TERRA in human cells can help promote telomere processing by inhibiting the 5'-3' exonuclease Exo1 through the Ku70 ...
Medical Education Building. The Paul L. Foster School of Medicine is a medical school in El Paso, Texas at Texas Tech University Health Sciences Center El Paso.The Paul L. Foster School of Medicine is the 9th medical school in the state of Texas, and the medical school is the first one to open in almost four decades.
In contrast, germ line and cancer cells possess an enzyme, telomerase, which prevents telomere degradation and maintains telomere integrity, causing these types of cells to be very long-lived. In humans, the role of subtelomere disorders is demonstrated in facioscapulohumeral muscular dystrophy (FSHD), Alzheimer's disease , epilepsy [ 17 ] and ...
It serves as the primary teaching hospital for the Texas Tech University Health Sciences Center (TTUHSC). [1] UMC had the first Level 1 Trauma Center in West Texas, the John A. Griswold Trauma Center, and it is still the only Level 1 Trauma Center in the region. [2] UMC's Timothy J. Harnar Burn Center is the only Burn Center in the region. [3]