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As an example, the cardiac action potential illustrates how differently shaped action potentials can be generated on membranes with voltage-sensitive calcium channels and different types of sodium/potassium channels. The second type of mathematical model is a simplification of the first type; the goal is not to reproduce the experimental data ...
Feedforward inputs that form synapses proximal to the soma and directly lead to action potentials; NMDA spikes generated in the more distal basal; Apical dendrites that depolarize the soma (usually insufficient to generate a somatic action potential) - Learns by growing new synapses - Inspired by the pyramidal cells in neocortex layers 2/3 and 5
This equation is the equation of a straight line for as a function of pH with a slope of () volt (pH has no units). This equation predicts lower E h {\displaystyle E_{h}} at higher pH values. This is observed for the reduction of O 2 into H 2 O, or OH − , and for reduction of H + into H 2 .
An action potential (also known as a nerve impulse or "spike" when in a neuron) is a series of quick changes in voltage across a cell membrane. An action potential occurs when the membrane potential of a specific cell rapidly rises and falls. [1] This depolarization then causes adjacent locations to similarly depolarize.
In Greek, the root rhe translates to "current or flow", and basi means "bottom or foundation": thus the rheobase is the minimum current that will produce an action potential or muscle contraction. Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). [ 2 ]
Saltatory conduction. In neuroscience, nerve conduction velocity (CV) is the speed at which an electrochemical impulse propagates down a neural pathway.Conduction velocities are affected by a wide array of factors, which include age, sex, and various medical conditions.
The slope of phase 0 on the action potential waveform (see figure 2) represents the maximum rate of voltage change of the cardiac action potential and is known as dV/dt max. In pacemaker cells (e.g. sinoatrial node cells ), however, the increase in membrane voltage is mainly due to activation of L-type calcium channels.
Figure B. is a recording of an actual action potential N.B. Actual recordings of action potentials are often distorted compared to the schematic view because of variations in electrophysiological techniques used to make the recording. In neurophysiology, a dendritic spike refers to an action potential generated in the dendrite of a neuron ...