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Around 50–100 million vertebrate animals are used in experiments annually. Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study.
The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (384–322 BCE) and Erasistratus (304–258 BCE) one of the first documented to perform experiments on nonhuman animals. [1] Galen, a physician in 2nd-century Rome, dissected pigs and goats, and is known as the "Father ...
Animals portal. v. t. e. Experiments involving non-human primates (NHPs) include toxicity testing for medical and non-medical substances; studies of infectious disease, such as HIV and hepatitis; neurological studies; behavior and cognition; reproduction; genetics; and xenotransplantation. Around 65,000 NHPs are used every year in the United ...
Monkey clinging to the cloth mother surrogate in fear test. Harry Frederick Harlow (October 31, 1905 – December 6, 1981) was an American psychologist best known for his maternal-separation, dependency needs, and social isolation experiments on rhesus monkeys, which manifested the importance of caregiving and companionship to social and cognitive development.
Despite a physical surface covering the cliff, the child hesitates to move forward. The visual cliff is an apparatus created by psychologists Eleanor J. Gibson and Richard D. Walk at Cornell University to investigate depth perception in human and other animal species. It consists of a sturdy surface that is flat but has the appearance of a ...
The Three Rs (3Rs) are guiding principles for more ethical use of animals in product testing and scientific research. They were first described by W. M. S. Russell and R. L. Burch in 1959. [1] The 3Rs are: Replacement: methods which avoid the use of animals in research. Reduction: use of methods that enable researchers to minimise the number of ...
Huffaker's mite experiment. In 1958, Carl B. Huffaker, an ecologist and agricultural entomologist at the University of California, Berkeley, did a series of experiments with predatory and herbivorous mite species to investigate predator–prey population dynamics. In these experiments, he created model universes with arrays of rubber balls and ...
Animal rights. Animal welfare. v. t. e. Rodents are commonly used in animal testing, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others. Mice are the most commonly used vertebrate species, due to their availability, size, low cost, ease of handling, and fast reproduction rate.