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Human Sar1A bound to GDP. The COPII coat consists of an inner layer – a flexible meshwork of Sar1, Sec23, and Sec24 – and an outer layer made of Sec13 and Sec31. [1] Sar1 resembles other Ras-family GTPases, with a core of six beta strands flanked by three alpha helices, and two flexible "switch domains".
A Cup of Coffee and New Shoes On (Albanian: Një filxhan kafe dhe këpucë të reja veshur) is a 2022 drama film written and directed by Gentian Koçi.It is inspired on a real case where 2 deaf brothers suffer from a degenerative disease that will eventually leave them blind.