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The mechanism of how exercise affects chemotherapy-induced peripheral neuropathy is not completely understood but may be related to maintaining muscle strength during treatment and/or increase ...
CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2] These symptoms can impair activities of daily living, such as typing or dressing, reduce balance, and increase risk of falls and hospitalizations. They can also give cause to reduce or discontinue chemotherapy.
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Women undergoing chemotherapy for breast cancer, who also began an aerobic exercise program at the same time, reported significant improvements in both cognitive function and quality of life.
The most general and maintainable advice for treating peripheral neuropathy and mononeuropathy would be to lead a balanced and healthy lifestyle, without good nutrition, exercise, avoiding mass exposure to toxins, balanced intake and absorption of vitamins and minerals, and reducing one’s alcoholic and smoking frequency. [4]