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  2. Bone remodeling - Wikipedia

    en.wikipedia.org/wiki/Bone_remodeling

    Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).

  3. Osteoclast - Wikipedia

    en.wikipedia.org/wiki/Osteoclast

    MMP-13 is believed to be involved in bone resorption and in osteoclast differentiation, as knockout mice revealed decreased osteoclast numbers, osteopetrosis, and decreased bone resorption. MMPs expressed by the osteoclast include MMP-9, -10, -12, and -14. apart from MMP-9, little is known about their relevance to the osteoclast, however, high ...

  4. Ossification - Wikipedia

    en.wikipedia.org/wiki/Ossification

    The canal of the nutrient foramen is directed away from more active end of bone when one end grows more than the other. When bone grows at same rate at both ends, the nutrient artery is perpendicular to the bone. Most other bones (e.g. vertebrae) also have primary ossification centers, and bone is laid down in a similar manner. Secondary centers

  5. Bone resorption - Wikipedia

    en.wikipedia.org/wiki/Bone_resorption

    Bone tissue is a dynamic system with active metabolism. [24] Bone tissue remodelling or bone remodeling is a successive chain of old bone matrix removal and its replacement with a new one. [25] These processes make a child’s skeleton grow and extend, while childhood is characterized by bone tissue growth rather than its resorption.

  6. Chondrogenesis - Wikipedia

    en.wikipedia.org/wiki/Chondrogenesis

    A spotted gar larva at 22 days stained for cartilage (blue) and bone (red). Chondrogenesis is the biological process through which cartilage tissue is formed and developed. . This intricate and tightly regulated cellular differentiation pathway plays a crucial role in skeletal development, as cartilage serves as a fundamental component of the embryonic skele

  7. Parathyroid hormone - Wikipedia

    en.wikipedia.org/wiki/Parathyroid_hormone

    Parathyroid hormone (PTH), also called parathormone or parathyrin, is a peptide hormone secreted by the parathyroid glands that regulates the serum calcium concentration through its effects on bone, kidney, and intestine. [5] PTH influences bone remodeling, which is an ongoing process in which bone tissue is alternately resorbed and rebuilt over

  8. Bone healing - Wikipedia

    en.wikipedia.org/wiki/Bone_healing

    Age, bone type, drug therapy and pre-existing bone pathology are factors that affect healing. The role of bone healing is to produce new bone without a scar as seen in other tissues which would be a structural weakness or deformity. [2] The process of the entire regeneration of the bone can depend on the angle of dislocation or fracture.

  9. Theories of craniofacial growth - Wikipedia

    en.wikipedia.org/wiki/Theories_of_Craniofacial...

    We see bone resorption happening on the outer side of the "V" of the bone and bone deposition happens on the inner side of the "V". Therefore, the movement of bone happens towards the open-end of the V. Enlow's Counterpart Principle [12] states that growth of one bone in the craniofacial area relates to the other bones in the same region ...