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Diffuse leptomeningeal glioneuronal tumor (DLGNT) is a rare, primary CNS tumor, classified as distinct entity in 2016 [1] and described as diffuse oligodendroglial-like leptomeningeal tumor of children in the 2016 classification of CNS neoplasms by the WHO., [2] Typically, it's considered juvenile tumors [3] but can occur in adults, [4] the average age of diagnosis is five years. [3]
Dysembryoplastic neuroepithelial tumour (DNT, DNET) is a type of brain tumor.Most commonly found in the temporal lobe, DNTs have been classified as benign tumours. [1] These are glioneuronal tumours comprising both glial and neuron cells and often have ties to focal cortical dysplasia.
Prior to AG's initiation, the most frequent and best-known types of rare glioneuronal tumors in the brain were dysembryoplastic neuroepithelial tumors and gangliogliomas. [4] In 2002, Wang and his group from the University of Texas recognised a novel neurological pattern in three cerebral hemispheric tumor cases and first published this rare ...
Glial tumor is a general term for numerous tumors of the central nervous system, including astrocytomas, ependymal tumors, Oligodendroglioma, and primitive neuroectodermal tumors. The World Health Organization (WHO) classifies tumors into different categories according to severity and recurrence. [ 1 ]
1.5 Glioneuronal and neuronal tumours 1.5.1 Ganglioglioma 1.5.2 Desmoplastic infantile ganglioglioma / desmoplastic infantile astrocytoma 1.5.3 Dysembryoplastic neuroepithelial tumor 1.5.4 Diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters 1.5.5 Papillary glioneuronal tumor 1.5.6 Rosette-forming glioneuronal tumor
As such, this is an exceptionally unusual diagnosis. The updated WHO guidelines published in 2007 recommends classifying such tumors for the time being as 'glioblastoma with oligodendroglioma component'. [8] It remains to be established whether or not these tumors carry a better prognosis than standard glioblastomas.
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