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Ruffini corpuscles respond to sustained pressure [4] and show very little adaptation. [5] Ruffinian endings are located in the deep layers of the skin, and register mechanical deformation within joints, more specifically angle change, with a specificity of up to 2.75 degrees, as well as continuous pressure states.
Angelo Ruffini (Pretare of Arquata del Tronto; 1864–1929) was an Italian histologist and embryologist. He studied medicine at the University of Bologna , where beginning in 1894 he taught classes in histology .
The Slowly Adapting type 2 (SA2) mechanoreceptors, with the Ruffini corpuscle end-organ (also known as the bulbous corpuscles), detect tension deep in the skin and fascia and respond to skin stretch, but have not been closely linked to either proprioceptive or mechanoreceptive roles in perception. [2]
Hada R (1990). "[Difference in responses of free nerve endings and Ruffini-type endings innervating the cat mandibular periosteum to square wave pressure stimuli, ramp mechanical stimuli and triangular vibrations]". Shikwa Gakuho. 90 (2): 161– 80. PMID 2135092. Textbook in Medical Physiology And Pathophysiology: Essentials and clinical problems.
Lamellar corpuscle (Pacinian corpuscle end-organ) The ultimately affected organ in a chain of events, such as a disease process (pathophysiology) or a drug's mechanism of action (sometimes called a target organ in this sense)
The density of tactile corpuscles, a type of mechanoreceptor that detects low-frequency vibrations, is greater in smaller fingers; [37] the same may hold for Merkel cells, which detect the static indentations important for fine spatial acuity. [36] Among children of the same age, those with smaller fingers also tend to have better tactile ...