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Pepto-Bismol was first sold in 1900 [20] by a doctor in New York. It was originally sold as a remedy for infant diarrhea by Norwich Pharmacal Company under the name "Bismosal: Mixture Cholera Infantum". [20] It was renamed Pepto-Bismol in 1919. Norwich Eaton Pharmaceuticals was acquired by Procter and Gamble in 1982. [21]
The active ingredient in Kaopectate has changed since its original creation. Originally, kaolinite was used as the adsorbent and pectin as the emollient. Attapulgite (a type of absorbent clay) replaced the kaolinite in the 1980s, but was banned by the U.S. Food and Drug Administration in a ruling made in April 2003.
The company’s mixture called Cholera Infantum, later renamed Pepto-Bismol, appeared for the first time in 1901. Its principal use was for infants with severe diarrhea. In 1907, Acetylsalicylic acid tablets were added to the company’s product line.
The cotton balls bring moisture into the bottle, which can damage the pills, so the National Library of Medicine actually recommends you take the cotton ball out. Related: Foods doctors won't eat ...
Bismuth subsalicylate is used to treat diarrhea; [9] it is the active ingredient in such "pink bismuth" preparations as Pepto-Bismol, as well as the 2004 reformulation of Kaopectate. It is also used to treat some other gastro-intestinal diseases like shigellosis [72] and cadmium poisoning. [9]
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
Pepto-Bismol over-the-counter drug for minor digestive system upset (acquired as part of Norwich Eaton Pharmaceuticals in 1982) Prilosec OTC (licensed from AstraZeneca) Rolaids (acquired in 2024 from Lil' Drug Store Products) Sangobion (acquired from Merck Group) Scope mouthwash; Seven Seas (acquired from Merck Group) Vicks cough and cold products
It is an active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate. Other derivatives include methyl salicylate, used as a liniment to soothe joint and muscle pain, and choline salicylate, which is used topically to relieve the pain of mouth ulcers.