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Severe allergic reactions to anesthetic medications are rare and are usually attributable to factors other than the anesthetic. Neuromuscular blocking agents, natural rubber latex, and antibiotics are the most common causes of serious allergic reactions during surgery. [2] The mortality rate from these reactions ranges between 3-9%. [3]
Epinephrine is also used as a bronchodilator for asthma if specific β 2 agonists are unavailable or ineffective. [39] Because of the high intrinsic efficacy (receptor binding ability) of epinephrine, high drug concentrations cause adverse side effects when treating asthma. The value of using nebulized epinephrine in acute asthma is unclear. [40]
Dental anesthesia (or dental anaesthesia) is the application of anesthesia to dentistry. It includes local anesthetics , sedation , and general anesthesia. Local anesthetic agents in dentistry
Hollywood fosters all kinds of myths about life threatening allergic reactions. There's nothing magical about anaphylactic choking that accelerates the time frame for losing consciousness to ten ...
Minor adverse effects from epinephrine include tremors, anxiety, headaches, and palpitations. [3] People on β-blockers may be resistant to the effects of epinephrine. [10] In this situation if epinephrine is not effective intravenous glucagon can be administered which has a mechanism of action independent of β-receptors. [10]
The US Food and Drug Administration approved the first nasal spray epinephrine drug for severe allergic reactions known as anaphylaxis, providing a needle-free alternative to EpiPens and similar ...
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
It is available mixed with a small amount of epinephrine to increase the duration of its action. [5] It typically begins working within 15 minutes and lasts for 2 to 8 hours. [5] [6] Possible side effects include sleepiness, muscle twitching, ringing in the ears, changes in vision, low blood pressure, and an irregular heart rate. [5]
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