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Atherosclerosis is characterized by the build-up of plaque inside your blood vessels. It can lead to stenosis, which is a narrowing of your artery walls. Plaque is a fatty substance made up of:
WS patients develop a considerable burden of atherosclerotic plaques in their coronary arteries and aorta: calcification of the aortic valve is also frequently observed. [138] These findings link excessive unrepaired DNA damage to premature aging and early atherosclerotic plaque development (see DNA damage theory of aging). [citation needed]
Find out why coronary calcification is bad for heart health and how to know ... Soft plaque is the most dangerous type of plaque because it can rupture suddenly, leading to blood clots and, in ...
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall. [1] [2]The material consists of mostly macrophage cells, [3] [4] or debris, containing lipids, calcium and a variable amount of fibrous connective tissue.
Atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. The term atherogenic is used for substances or processes that cause atherosclerosis. Micrograph showing hyaline arteriolosclerosis in the kidney. PAS stain.
One of the principal causes of arterial stiffening with age is vascular calcification. Vascular calcification is the deposition of mineral in the form of calcium phosphate salts in the smooth muscle-rich medial layer of large arteries including the aorta. DNA damage, especially oxidative DNA damage, causes accelerated vascular calcification. [11]
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart.