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Dihydrotestosterone (DHT) is a metabolite of testosterone, and a more potent androgen than testosterone in that it binds more strongly to androgen receptors. It is produced in the skin and reproductive tissue. A4 and testosterone can also have an extra hydroxyl (-OH) or keton (=O) group bound on position 11.
Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5α-dihydrotestosterone (5α-DHT) by the cytoplasmic enzyme 5α-reductase. 5α-DHT binds to the same androgen receptor even more strongly than testosterone, so that its androgenic potency is about 5 ...
Testosterone is the primary androgen — or male hormone — in your body. Low testosterone affects up to 39 percent of adult men in the US over the age of 45, and becomes increasingly prevalent ...
In many contexts, the two main classes of sex hormones are androgens and estrogens, of which the most important human derivatives are testosterone and estradiol, respectively. Other contexts will include progestogens as a third class of sex steroids, distinct from androgens and estrogens. [5]
Research on women and testosterone has been limited, but as more is done, experts are seeing that the hormone affects the female sex drive, just as it does the male. It also plays an essential ...
The body converts some testosterone ito dihydrotestosterone , another androgen. DHT binds to androgen receptors in hair follicles, causing them to shrink. DHT binds to androgen receptors in hair ...
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