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The formula was originally developed by Drs. Loretta Mayer and Cheryl Dyer as part of a research program studying heart disease in post-menopausal women using menopausal mice. [5] The first active ingredient of ContraPest is 4-vinylcyclohexene diepoxide (VCD), which causes destruction of the antral follicle during folliculogenesis in the female ...
Peptidoglycan. The peptidoglycan layer within the bacterial cell wall is a crystal lattice structure formed from linear chains of two alternating amino sugars, namely N-acetylglucosamine (GlcNAc or NAG) and N-acetylmuramic acid (MurNAc or NAM).
Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides.Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin, avoparcin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin.
Lysozyme (EC 3.2.1.17, muramidase, N-acetylmuramide glycanhydrolase; systematic name peptidoglycan N-acetylmuramoylhydrolase) is an antimicrobial enzyme produced by animals that forms part of the innate immune system. It is a glycoside hydrolase that catalyzes the following process:
Human, [18] [58] mouse, [57] and porcine [74] PGLYRP2 are enzymes, N-acetylmuramoyl-L-alanine amidases, that hydrolyze the amide bond between the MurNAc and L-alanine, the first amino acid in the stem peptide in bacterial cell wall peptidoglycan. The minimal peptidoglycan fragment hydrolyzed by PGLYRP2 is MurNAc-tripeptide. [58]
d-CON is an America brand of rodent control products, which is distributed and owned in the United States by the UK-based consumer goods company Reckitt.. The brand includes traps and baits for use around the home for trapping and killing some rats and mice.
This interaction causes decrease of TNF-α (tumor necrosis factor-α) production by alveolar macrophages stimulated with peptidoglycan. [17] SP-A and SP-D can modulate cytokine production. They modulate the production of oxygen and nitrogen reactive species which are very important for phagocytic cells.
Typical rat poison bait station (Germany, 2010) Rodenticides are chemicals made and sold for the purpose of killing rodents.While commonly referred to as "rat poison", rodenticides are also used to kill mice, woodchucks, chipmunks, porcupines, nutria, beavers, [1] and voles.