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  2. Lipoic acid - Wikipedia

    en.wikipedia.org/wiki/Lipoic_acid

    Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). [3] ALA, which is made in animals normally, is essential for aerobic metabolism. It is also available as a dietary supplement or pharmaceutical drug in some countries.

  3. Neuropathic pain - Wikipedia

    en.wikipedia.org/wiki/Neuropathic_pain

    A 2007 review of studies found that injected administration of alpha lipoic acid (ALA) was found to reduce the various symptoms of peripheral diabetic neuropathy. [73]

  4. Peripheral neuropathy - Wikipedia

    en.wikipedia.org/wiki/Peripheral_neuropathy

    Alpha lipoic acid (ALA) with benfotiamine is a proposed pathogenic treatment for painful diabetic neuropathy only. [119] The results of two systematic reviews state that oral ALA produced no clinically significant benefit, intravenous ALA administered over three weeks may improve symptoms and that long-term treatment has not been investigated ...

  5. Peripheral mononeuropathy - Wikipedia

    en.wikipedia.org/wiki/Peripheral_mononeuropathy

    Peripheral neuropathy and mononeuropathy are common neurological disorders, with a diverse range of variables and causes to conclude a diagnosis. [2] Neuropathy has three sub-classifications; mononeuropathy is a result of an entrapped or traumatised nerve or nerve area, Mononeuropathy multiplex is linked to chronic diseases like leprosy, and ...

  6. Adrenoleukodystrophy - Wikipedia

    en.wikipedia.org/wiki/Adrenoleukodystrophy

    Aldixyl®: In 2016, based on studies developed in recent years in the field of adrenoleukodystrophy and adrenomyelouropathy, a mixture was developed that adds to GTO, GTE and CLA, a mixture of powerful antioxidants at high dosages containing alpha lipoic acid (ALA), reduced L- glutathione and Vitamin E (α- tocopherol).

  7. Benfotiamine - Wikipedia

    en.wikipedia.org/wiki/Benfotiamine

    Benfotiamine has been studied in laboratory models of diabetic retinopathy, neuropathy, and nephropathy. [10] A 2021 review of its use for diabetic polyneuropathy described two clinical trials which showed improvements in neuropathic pain and neuropathic symptoms scores, the latter of which showed a dose-response effect. [4]

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