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Keratin (/ ˈ k ɛr ə t ɪ n / [1] [2]) is one of a family of structural fibrous proteins also known as scleroproteins. It is the key structural material making up scales , hair , nails , feathers , horns , claws , hooves , and the outer layer of skin in vertebrates.
[1] [2] These two groups of keratins were named as type I and type II keratins. [2] These two categories also represent the first two categories of the superfamily of intermediate filament proteins. Keratins in this table are classified in the first two columns according to the nomenclature established in 2006. [3]
16678 Ensembl ENSG00000167768 ENSMUSG00000046834 UniProt P04264 P04104 RefSeq (mRNA) NM_006121 NM_008473 RefSeq (protein) NP_006112 NP_032499 Location (UCSC) Chr 12: 52.67 – 52.68 Mb Chr 15: 101.75 – 101.76 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratin 1 is a Type II intermediate filament (IFs) of the intracytoplasmatic cytoskeleton. Is co-expressed with and binds to ...
Keratins belong to two types - acidic Type I and neutral-basic Type II, further categorized into Type I a and b, and Type II a and b. The initial step in forming keratin is the alignment of type I and type II keratin polypeptides to create a heterodimer, which then aggregates into higher-order structural units. [2]
64818 Ensembl ENSG00000205426 ENSMUSG00000067615 UniProt Q14533 Q9ERE2 RefSeq (mRNA) NM_002281 NM_001166157 RefSeq (protein) NP_002272 NP_001159629 Location (UCSC) Chr 12: 52.29 – 52.29 Mb Chr 15: 101.36 – 101.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratin, type II cuticular Hb1 is a protein that in humans is encoded by the KRT81 gene. The protein encoded by this gene ...
3881 16671 Ensembl ENSG00000094796 ENSG00000262993 ENSMUSG00000057723 UniProt Q15323 Q61897 RefSeq (mRNA) NM_002277 NM_013570 RefSeq (protein) NP_002268 NP_038598 Location (UCSC) Chr 17: 41.39 – 41.4 Mb Chr 11: 99.91 – 99.92 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31 gene. Function The protein ...
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223917 Ensembl ENSG00000185640 ENSMUSG00000061397 UniProt Q5XKE5 Q8VED5 RefSeq (mRNA) NM_175834 NM_146063 RefSeq (protein) NP_787028 NP_666175 Location (UCSC) Chr 12: 52.82 – 52.83 Mb Chr 15: 101.84 – 101.85 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratin 79 also known as KRT79 is a protein which humans is encoded by the KRT79 gene. Function Keratins, such as KRT79, are ...