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Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
To avoid misdiagnosis as nail psoriasis, lichen planus, contact dermatitis, nail bed tumors such as melanoma, trauma, or yellow nail syndrome, laboratory confirmation may be necessary. [2] Other conditions that may appear similar to onychomycosis include: psoriasis, normal aging, green nail syndrome, yellow nail syndrome, and chronic paronychia ...
Human leukocyte antigen (HLA) alleles associated with conditions of or affecting the human integumentary system Condition Associated HLA allele(s) Fixed drug eruption: B22 Lichen planus: DR1 DR2 DRw9 DR10 Bw15 B8 Psoriasis: Cw6 DR406 Psoriatic arthritis: B27 Ankylosing spondylitis: B27 Reactive arthritis: B27 Acute anterior uveitis: B27 Behçet ...
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The exact cause of subungual melanomas is not known, but it doesn’t seem to be linked to sun exposure. Having certain characteristics, including an age between 50 to 70, darker skin, and a ...
Lichenoid eruptions are dermatoses related to the unique, common inflammatory disorder lichen planus, which affects the skin, mucous membranes, nails, and hair. [74] [75] [76] Annular lichen planus Lichen planus actinicus; Atrophic lichen planus; Bullous lichen planus (vesiculobullous lichen planus) Erosive lichen planus
Melanonychia is a black or brown pigmentation of a nail, and may be present as a normal finding on many digits in Afro-Caribbeans, as a result of trauma, systemic disease, or medications, or as a postinflammatory event from such localized events as lichen planus or fixed drug eruption.
Clubbing is associated with lung cancer, lung infections, interstitial lung disease, cystic fibrosis, or cardiovascular disease. [5] Clubbing may also run in families, [5] and occur unassociated with other medical problems. [6] [7] Clubbing has been recognized as a sign of disease since the time of Hippocrates. [5]