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Dakin's solution is a dilute solution of sodium hypochlorite (0.4% to 0.5%) and other stabilizing ingredients, traditionally used as an antiseptic, e.g. to cleanse wounds in order to prevent infection. [1] The preparation was for a time called also Carrel–Dakin solution or Carrel–Dakin fluid. [2]
A clinical evaluation of Prontosan wound cleanser was undertaken with ten community care patients where saline had been used for at least one month previously on wounds that had a mean duration of 2.6 years. [37] The findings include; an overall reduction in wound size, a reduction in malodour, reduction or elimination of wound pain.
For these purposes PVP-I has been formulated at concentrations of 7.5–10.0% in solution, spray, surgical scrub, ointment, and swab dosage forms; however, use of 10% povidone-iodine though recommended, is infrequently used, as it is poorly accepted by health care workers and is excessively slow to dry. [11] [12]
The polyethylene glycol provides a moist environment allowing the iodine to reach the wound. [4] After a few days the dressing has a tendency to dry out, and must be changed often. Left on too long, it can engage with wound tissue and wound secretions when drier, and be more difficult to remove. [4]
Liquid bandages are suitable for clean cuts that close easily and shallow small wounds, as it will help both sides of the wound to bond and produce a suture-like effect. Due to the drying of liquid wound dressing, it will form a nonelastic film on the wound and cannot absorb tissue fluid. If the wound area is too large, it will actually hinder ...
Chloroxylenol, also known as para-chloro-meta-xylenol (PCMX), is a chlorine substituted phenol with a white to off-white appearance and a phenolic odor.. The discovery of chloroxylenol was the result of efforts to produce improved antiseptics that began at the end of the 1800s, when scientists gradually realized that more substituted and more lipophilic phenols are less toxic, less irritant ...