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Levofloxacin, sold under the brand name Levaquin among others, is a broad-spectrum antibiotic of the fluoroquinolone drug class. [6] It is the left-handed isomer of the medication ofloxacin .
The IC 50 of a drug can be determined by constructing a dose-response curve and examining the effect of different concentrations of antagonist on reversing agonist activity. IC 50 values can be calculated for a given antagonist by determining the concentration needed to inhibit half of the maximum biological response of the agonist. [4]
An illustration shows the different effects of the bacteriostatic agent and bactericidal agent. A bacteriostatic agent or bacteriostat, abbreviated Bstatic, is a biological or chemical agent that stops bacteria from reproducing, while not necessarily killing them otherwise.
Levofloxacin, which is marketed under the brand name Levaquin in the U.S. and Tavanic in the EU, is often prescribed for pneumonia, urinary tract infections and infections of the abdomen.
The initial buzz and immediate effects of alcohol may be familiar. Here’s how the long-term consequences of excessive drinking can gradually take a toll on your health. 1.
drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use; physical dependence – dependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)
Intoxication does have real physiological effects, such as altering a drinker's perception of space and time, reducing psychomotor skills, and disrupting equilibrium. [74] But some effects and the degree of the effects that are attributed to alcohol can be due to the expectations rather than the substance itself, [75] similar to the placebo ...
The effects of the toxicants depends on the dose, threshold and duration. The effects of toxicity are: [citation needed] Minor structural deformities - e.g. Anticonvulsant drugs, Warfarin, Retinoic Acid derivatives; Major structural deformities - e.g. DES (diethylstilbestrol), cigarette smoking; Growth Retardation - e.g. Alcohol ...