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Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions. [1] Impaired ability of damaged motor neurons to regulate descending pathways gives rise to disordered spinal reflexes , increased excitability of muscle spindles ...
Lorazepam, belongs to group of medicine named benzodiazepines. It is a commonly used medicine to treat anxiety disorders. Catatonic depression is a severe but manageable subtype of depression. Benzodiazepines, such as lorazepam, are often prescribed as the first-line treatment for catatonia. These medications contain anxiety-relieving and ...
altered muscle tone (hypotonia or hypertonia) – a decrease or increase in the baseline level of muscle activity; decreased endurance; exaggerated deep tendon reflexes including spasticity, and clonus (a series of involuntary rapid muscle contractions) Such signs are collectively termed the "upper motor neuron syndrome".
Commonly reported symptoms are initial truncal hypotonia, subsequent appendicular hypertonia, bradykinesia, cogwheel rigidity, generalized dystonia, and marked diurnal fluctuation. Other reported clinical features include difficulty in swallowing, oculogyric crises , somnolence , irritability , hyperthermia , and seizures .
Hyperekplexia (/ ˌ h aɪ. p ər. ɛ k ˈ p l ɛ k. s i. ə /; "exaggerated surprise") is a neurological disorder characterized by a pronounced startle response to tactile or acoustic stimuli and an ensuing period of hypertonia. The hypertonia may be predominantly truncal, attenuated during sleep, or less prominent after one year of age.
Another form of hypertonia is paratonia, which is associated with dementia. [5] Hypotonia is seen in lower motor neuron disease like poliomyelitis. Hypotonia can present clinically as muscle flaccidity, where the limbs appear floppy, stretch reflex responses are decreased, and the limb's resistance to passive movement is also decreased. [1]
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure. [1] While earlier definitions emphasized the inability to experience pleasure, anhedonia is currently used by researchers to refer to reduced motivation, reduced anticipatory pleasure (wanting), reduced consummatory pleasure (liking), and deficits in reinforcement learning.