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Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis, cholestasis of pregnancy, jaundice of pregnancy, and prurigo gravidarum, [1] is a medical condition in which cholestasis occurs during pregnancy. [2] It typically presents with itching and can lead to complications for both mother and fetus. [2]
The signs and symptoms of cholestasis vary according to the cause. In case of sudden onset, the disease is likely to be acute, while the gradual appearance of symptoms suggests chronic pathology. [2] In many cases, patients may experience pain in the abdominal area.
This is a list of conditions that can cause posthepatic jaundice: Choledocholithiasis (common bile duct gallstones). It is the most common cause of obstructive jaundice. Pancreatic cancer of the pancreatic head; Biliary tract strictures; Biliary atresia; Primary biliary cholangitis; Cholestasis of pregnancy; Acute Pancreatitis; Chronic Pancreatitis
Bleeding before childbirth is that which occurs after 24 weeks of pregnancy. [4] Bleeding may be vaginal or less commonly into the abdominal cavity. Bleeding which occurs before 24 weeks is known as early pregnancy bleeding. Causes of bleeding before and during childbirth include cervicitis, placenta previa, placental abruption and uterine rupture.
Extrapyramidal symptoms [Note 2] Weight gain; ... Cholestatic jaundice; Liver injury; ... False-positive pregnancy tests; Allergic reaction; Fits;
Signs and symptoms of pregnancy are common, benign conditions that result from the changes to the body that occur during pregnancy. Signs and symptoms of pregnancy typically change as pregnancy progresses, although several symptoms may be present throughout. Depending on severity, common symptoms in pregnancy can develop into complications ...
Additional symptoms may vary based on the cause of neonatal cholestasis. For example, if a patient’s symptoms are caused by a choledochal cyst, they may present with abdominal pain, vomiting, and a palpable abdominal mass. [4] Patients with alpha-1 antitrypsin deficiency may present with hepatomegaly and elevated liver enzymes. [9]
Jaundice of the skin or eyes is an important physical finding in biliary obstruction. Jaundice and/or clay-colored stool may raise suspicion of choledocholithiasis or even gallstone pancreatitis. [1] If the above symptoms coincide with fever and chills, the diagnosis of ascending cholangitis may also be considered.