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Rooney said these findings may one day lead to new treatment options for rheumatoid arthritis. “Our findings suggest that certain bacteria in the gut microbiome may be involved in triggering the ...
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1]
OMERACT has achieved consensus on Core Outcome Sets for conditions such as rheumatoid arthritis, osteoarthritis, and osteoporosis. [5] The measures endorsed by OMERACT are widely adopted in clinical trials and systematic reviews, contributing to standardization in the field. [2]
Laboratory findings are usually normal. Blood tests may show an elevation of the ESR and CRP, but are otherwise unremarkable. Rheumatoid factor may be present especially in the group that is likely to develop rheumatoid arthritis. Proposed classification by Guerne and Weismann in 1992: [8]
Researchers believe there may be a link between long-term vitamin D deficiency and the development of autoimmune conditions, such as type 1 diabetes and rheumatoid arthritis, but more research is ...
Anti-CCP is also very useful in the early diagnosis of rheumatoid arthritis in high-risk groups, such as relatives of RA patients, [19] although Silman and co-workers found that the concordance rate of developing RA was 15.4% among identical (monozygotic) twins and was 3.6% among fraternal (dizygotic) twins. [20]
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