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Chlortalidone, also known as chlorthalidone, is a thiazide-like diuretic drug [1] used to treat high blood pressure, swelling (such as occurs in heart failure, liver failure, and nephrotic syndrome), diabetes insipidus, and renal tubular acidosis.
Spironolactone can cause breast pain and breast enlargement in women. [ 128 ] [ 129 ] This is "probably because of estrogenic effects on target tissue." [ 111 ] At low doses, breast tenderness has been reported in only 5% of women, but at high doses, it has been reported in up to 40% of women.
The term "thiazide" is also often used for drugs with a similar action that do not have the thiazide chemical structure, such as chlorthalidone, metolazone and indapamide. These agents are more properly termed thiazide-like diuretics. [citation needed] Thiazide diuretics also increase calcium reabsorption at the distal tubule.
According to Ruth Oratz, M.D., breast medical oncologist at NYU Langone Health’s Perlmutter Cancer Center, other rare breast-related causes for pain include: Benign cyst Changes resulted to ...
Breast pain that is not linked to a menstrual cycle is called noncyclic breast pain. Noncyclical breast pain has various causes and is harder to diagnose and frequently the root cause is outside the breast. Some degree of non-cyclical breast tenderness can normally be present due to hormonal changes in puberty (both in girls and boys), in ...
Post-mastectomy pain syndrome is a chronic neuropathic pain that usually manifests as continuous pain in the arm, axilla, chest wall, and breast region. [3] Pain is most likely to start after surgery, [3] although adjuvant therapy, such as chemotherapy or radiation therapy, may sometimes cause new symptoms to appear. [4]
The periareolar glands of Montgomery in the breast are also called Montgomery tubercles or Morgagni tubercles. These periareolar glands are small, papular tissue projections at the edge of the areola (nipple).Obstruction of the Montgomery tubercles may result in an acute inflammation, a clear or light brownish fluid may drain out of the areola (nipple discharge), and an subareolar mass may ...
[5] [6] [7] Mammoplasia may be due to breast engorgement, which is temporary enlargement of the breasts caused by the production and storage of breast milk in association with lactation and/or galactorrhea (excessive or inappropriate production of milk). [8] Mastodynia (breast tenderness/pain) frequently co-occurs with mammoplasia. [9] [10]