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An infantile hemangioma (IH), sometimes called a strawberry mark due to appearance, is a type of benign vascular tumor or anomaly that affects babies. [1] [2] Other names include capillary hemangioma, [6] "strawberry hemangioma", [7]: 593 strawberry birthmark [8] and strawberry nevus. [6] and formerly known as a cavernous hemangioma.
A hemangioma or haemangioma is a usually benign vascular tumor derived from blood vessel cell types. The most common form, seen in infants, is an infantile hemangioma , known colloquially as a "strawberry mark", most commonly presenting on the skin at birth or in the first weeks of life.
Infantile hemangioma is the most common vascular tumor. It is a benign tumor, which occurs in 4-5% of Caucasian infants, but rarely in dark skinned infants. [6] It occurs in 20% of low weight premature infants and 2.2 to 4.5 times more frequently in females. [7]
[2]: 599 These tumors were reclassified by Dr. Weiss in 1996 as "spindle cell hemangioma", rather than hemangioendothelioma, due to the excellent prognosis observed in a group of 78 patients. [ 5 ] Retiform hemangioendothelioma (also known as a "Hobnail hemangioendothelioma" [ 3 ] ) is a low-grade angiosarcoma , first described in 1994 ...
Infantile hemangiomas are the most common type of vascular tumor to affect babies, [4] accounting for 90% of hemangiomas. [5] They are characterised by the abnormal proliferation of endothelial cells and of deviant blood vessel formation or architecture. [6] Hypoxic stress seems to be a major trigger for this. [7]
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Histology must be used to make the diagnosis because the tumor may be hard to differentiate from other neoplasms with similar characteristics. [7] Histologically, hemangiopericytoma is characterized by staghorn-shaped blood vessels and sponge-like sinusoidal vasculature that are randomly linked and encircled by ovoid, short spindle-shaped cells. [8]
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