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A 3D cell culture is an artificially created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Unlike 2D environments (e.g. a Petri dish), a 3D cell culture allows cells in vitro to grow in all directions, similar to how they would in vivo. [1]
CompuCell3D [1] (CC3D) is a three-dimensional C++ and Python software problem solving environment for simulations of biocomplexity problems, integrating multiple mathematical [morphogenesis] models. These include the cellular Potts model (CPM) or Glazier-Graner-Hogeweg model (GGH) (originally developed by James A. Glazier, François Graner and ...
Cellular oxygen is reduced to the radical, creating reactive oxygen species, which can damage DNA and other components of the mitochondria. [ 39 ] Rotenone is used in biomedical research to study the oxygen consumption rate of cells, usually in combination with antimycin A (an electron transport chain Complex III inhibitor), oligomycin (an ATP ...
Regular phylogenetic tree – Generally called a dendrogram, it is a diagram with straight lines representing a tree. It would show a column of nodes representing individual taxa, and the remaining nodes represent the clusters to which the data belong, with the arrows representing the distance: a way to measure how different they are ...
Cellular respiration is the process of oxidizing biological fuels using an inorganic electron acceptor, such as oxygen, to drive production of adenosine triphosphate (ATP), which contains energy. Cellular respiration may be described as a set of metabolic reactions and processes that take place in the cells of organisms to convert chemical ...
The eukaryotic cell cycle is very complex and is one of the most studied topics, since its misregulation leads to cancers. It is possibly a good example of a mathematical model as it deals with simple calculus but gives valid results. Two research groups [1] [2] have produced several models of the cell cycle simulating several organisms. They ...
Creating a cellular model has been a particularly challenging task of systems biology and mathematical biology. It involves the use of computer simulations of the many cellular subsystems such as the networks of metabolites, enzymes which comprise metabolism and transcription, translation, regulation and induction of gene regulatory networks. [4]
Organisms that consume the chemosynthetic bacteria can take in the glucose and use oxygen to perform cellular respiration, similar to herbivores consuming producers. One of the factors that controls primary production is the amount of energy that enters the producer(s), which can be measured using productivity.