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The core-matrix theory of thalamus, first proposed by Ted Jones in 1998, states that neurons in the thalamus belong to either a parvalbumin-immunopositive core of precisely projecting neurons, or to a calbindin-immunopositive matrix of diffusely and widely projecting neurons.
The thalamus is connected to the cerebral cortex via the thalamocortical radiations. [28] The spinothalamic tract is a sensory pathway originating in the spinal cord. It transmits information to the thalamus about pain, temperature, itch and crude touch.
It is proposed that core relay cells and matrix cells projecting from the dorsal thalamus allow for synchronization of cortical and thalamic cells during "high-frequency oscillations that underlie discrete conscious events", [7] though this is a heavily debated area of research.
The loop involves connections between the cortex, the basal ganglia, the thalamus, and back to the cortex. It is of particular relevance to hyperkinetic and hypokinetic movement disorders , such as Parkinson's disease and Huntington's disease , [ 1 ] as well as to mental disorders of control, such as attention deficit hyperactivity disorder ...
An important component of the system is the reticular formation, a group of neuron-clusters scattered diffusely through the core of the lower brain. Reticular neurons send signals to the thalamus, which in turn sends activity-level-controlling signals to every part of the cortex.
Beneath the lateral ventricles is the thalamus and to the front and below is the hypothalamus. The hypothalamus leads on to the pituitary gland. At the back of the thalamus is the brainstem. [27] The basal ganglia, also called basal nuclei, are a set of structures deep within the hemispheres involved in behaviour and movement regulation. [28]
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The diencephalon encloses a cavity called the third ventricle. The thalamus serves as a relay centre for sensory and motor impulses between the spinal cord and medulla oblongata, and the cerebrum. It recognizes sensory impulses of heat, cold, pain, pressure etc. The floor of the third ventricle is called the hypothalamus.