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Procainamide (PCA) is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias. It is a sodium channel blocker of cardiomyocytes; thus it is classified by the Vaughan Williams classification system as class Ia. In addition to blocking the I Na current, it inhibits the I Kr rectifier K+ current. [1]
Chronic superficial keratitis (CSK), also known as pannus or Uberreiter's disease, is an inflammatory condition of the cornea in dogs, particularly seen in the German Shepherd. Both eyes are usually affected. The corneas gradually become pigmented and infiltrated by blood vessels, and the dog may eventually become blind.
Sudden acquired retinal degeneration syndrome (SARDS) is a disease in dogs causing sudden blindness. It can occur in any breed, but female dogs may be predisposed. [1] Approximately 4000 cases are seen in the United States annually. [2]
amitriptyline – tricyclic antidepressant used to treat separation anxiety, excessive grooming dogs and cats; amlodipine – calcium channel blocker used to decrease blood pressure; amoxicillin – antibacterial; apomorphine – emetic (used to induce vomiting) artificial tears – lubricant eye drops used as a tear supplement
Sodium channel blockers are also used as local anesthetics and anticonvulsants. [5] Sodium channel blockers have been proposed for use in the treatment of cystic fibrosis, [6] but current evidence is mixed. [7] It has been suggested that the analgesic effects of some antidepressants may be mediated in part via sodium channel blockade. [8]
“Cherry eye is a common eye condition in dogs where a gland in the third eyelid pops out and swells up, making it look like a red, swollen ‘cherry’ in the corner of the eye,” says Dr. Hood.
The least common type of glaucoma in dogs is primary open-angle glaucoma (POAG), although this is the most common type that affects humans. [1] In the Beagle, POAG is an inherited autosomal recessive trait. [2] Secondary glaucomas occur when other eye diseases alter the flow of aqueous humor either into or out of the eye.
The dark blue, teal, and gold tapetum lucidum from the eye of a cow Retina of a mongrel dog with strong tapetal reflex. The tapetum lucidum (Latin for 'bright tapestry, coverlet'; / t ə ˈ p iː t əm ˈ l uː s ɪ d əm / tə-PEE-təm LOO-sih-dəm; pl.: tapeta lucida) [1] is a layer of tissue in the eye of many vertebrates and some other animals.