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Postinflammatory hypopigmentation is a highly prevalent pigmentary disease. It can happen to any type of skin. Nonetheless, individuals with darker skin seem to have it more frequently and visibly, perhaps due to the color contrast with their natural skin. The incidence of postinflammatory hypopigmentation is the same for both sexes. [2]
The pain is often described as stabbing or burning, or abnormal skin sensations such as tingling or itchiness. In some individuals, the pain is more severe during times of rest or at night. The signs and symptoms of small fiber neuropathy can occur at any point in life depending on the underlying cause.
Therapy for notalgia paresthetica is directed at controlling symptoms, as no cure exists for the condition. Available treatments include local anesthetics, topical capsaicin, [6] [7] topical corticosteroids, [8] hydroxyzine, oxcarbazepine, palmitoylethanolamide and gabapentin. Paravertebral nerve block and botulinum toxin injections may also be ...
The gold standard for diagnosing small fiber neuropathy as the etiology of neuropathic pain is skin biopsy. Sudomotor assessment, through electrochemical skin conductance , an accurate objective technique, could be considered as a good screening tool to limit skin biopsy in patients in whom it is not suitable.
Skin pigmentation is frequently caused by sun exposure. To protect itself against UV radiation from the sun, the body makes more melanin. As a result, the skin may become more pigmented to protect it from the sun's rays. [4] The pigmentation of the skin may also be lightened by certain drugs.
Neuritis (/ nj ʊəˈr aɪ t ɪ s /), from the Greek νεῦρον), [1] is inflammation of a nerve [2] or the general inflammation of the peripheral nervous system.Inflammation, and frequently concomitant demyelination, [3] [4] [5] cause impaired transmission of neural signals and leads to aberrant nerve function.