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Primary central nervous system lymphoma (PCNSL), also termed primary diffuse large B-cell lymphoma of the central nervous system (DLBCL-CNS), [2] is a primary intracranial tumor appearing mostly in patients with severe immunodeficiency (typically patients with AIDS). It is a subtype and one of the most aggressive of the diffuse large B-cell ...
Metastatic brain cancer is over six times more common than primary brain cancer, as it occurs in about 10–30% of all people with cancer. [1] This is a list of notable people who have had a primary or metastatic brain tumor (either benign or malignant) at some time in their lives, as confirmed by public information. Tumor type and survival ...
The Central Nervous System – International Prognostic Index (CNS-IPI) has emerged as a valuable tool for risk stratification. Developed by the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL) in 2016, the CNS-IPI integrates factors from the International Prognostic Index (IPI) along with additional considerations such as kidney and ...
The Central Brain Tumor Registry of the United States (CBTRUS) is the primary national database of malignant and benign tumors of the brain, "other central nervous system (CNS), tumors of the pituitary and pineal glands, olfactory tumors of the nasal cavity, and brain lymphoma and leukemia." [1] A non-profit, it was established in 1992. [2] [3 ...
Primary diffuse large B-cell lymphoma of the central nervous system (DLBCL-CNS, also termed primary central nervous system lymphoma [PCNSL]) is a DLBCL in which diffuse patterns of neoplastic B-cells with centroblastic, immunoblastic, or poorly differentiated features infiltrate the brain, spinal cord, leptomeninges, or eye. [24]
Lymphoma may present with certain nonspecific symptoms; if the symptoms are persistent, an evaluation to determine their cause, including possible lymphoma, should be undertaken. Lymphadenopathy [19] [20] or swelling of lymph nodes, is the primary presentation in lymphoma. It is generally painless.