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  2. Gonadotropin-releasing hormone - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing_hormone

    Gonadotropin-releasing hormone (GnRH) is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is a tropic peptide hormone synthesized and released from GnRH neurons within the hypothalamus .

  3. GnRH neuron - Wikipedia

    en.wikipedia.org/wiki/GnRH_Neuron

    The strongest activator of GnRH neurons is a hormone called kisspeptin. [16] GnRH neurons also integrate information from the body through hormones like neuropeptide Y [17] and adiponectin. [18] These hormones provide the GnRH neurons with information about the body's status to help determine whether reproduction should be prioritized or ...

  4. Hypothalamic–pituitary–gonadal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Fluctuations in this axis cause changes in the hormones produced by each gland and have various local and systemic effects on the body. The axis controls development, reproduction, and aging in animals. Gonadotropin-releasing hormone (GnRH) is secreted from the hypothalamus by GnRH-expressing neurons.

  5. Folliculogenesis - Wikipedia

    en.wikipedia.org/wiki/Folliculogenesis

    Five hormones participate in an intricate process of positive and negative feedback to regulate folliculogenesis. They are: gonadotropin-releasing hormone (GnRH) secreted by the hypothalamus; two gonadotropins: follicle-stimulating hormone (FSH) luteinizing hormone (LH) estrogen; progesterone

  6. Gonadotropin-releasing hormone family - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing...

    The gonadotropin-releasing hormones (GnRH) (gonadoliberin) [1] are a family of peptides that play a pivotal role in reproduction. The main function of GnRH is to act on the pituitary to stimulate the synthesis and secretion of luteinizing and follicle-stimulating hormones, but GnRH also acts on the brain, retina, sympathetic nervous system, gonads, and placenta in certain species.

  7. Gonadotropin-releasing hormone agonist - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing...

    A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones. [1] They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of hormone-sensitive cancers such as prostate cancer and breast cancer, certain gynecological disorders like heavy periods and endometriosis ...

  8. Gonadotropic cell - Wikipedia

    en.wikipedia.org/wiki/Gonadotropic_cell

    GnRH is a hormone released by the hypothalamus, and it is responsible for signaling gonadotrophs to release gonadotropins FSH and LH. GnRH binds to gonadotropin-releasing hormone receptors (GnRHR), which is a G-protein coupled receptor , and signals the oscillation of calcium that hyperpolarizes gonadotropic cell membranes. [ 6 ]

  9. Gonadarche - Wikipedia

    en.wikipedia.org/wiki/Gonadarche

    Gonadarche marks the beginning of puberty and it is the process in which gonads, or the primary reproductive organs, mature, following stimulation of gonadotropin hormone-releasing hormone (GnRH) release in the hypothalamus. [6] The release of GnRH triggers a release of hormones that activate the maturation of the ovary and testis. [3]