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Agglutination is a reaction in which particles (as red blood cells or bacteria) suspended in a liquid collect into clumps usually as a response to a specific antibody. Agglutination(clumping) of red blood cells. This occurs in biology in two main examples: The clumping of cells such as bacteria or red blood cells in the presence of an antibody ...
The antigens and antibodies combine by a process called agglutination. It is the fundamental reaction in the body by which the body is protected from complex foreign molecules, such as pathogens and their chemical toxins. In the blood, the antigens are specifically and with high affinity bound by antibodies to form an antigen-antibody complex.
This leads to a markedly decreased red blood cell count and hematocrit and markedly elevated mean cell volume and mean cell hemoglobin concentration. [5]: 32–3 Red cell agglutination also interferes with routine methods for blood typing and blood compatibility testing, which rely on agglutination reactions. People with red cell agglutination ...
As a result, the blood of a host applied to a diagnostic kit causes the aggregation of the pathogenic particles due to the antigen-agglutinin interaction. Conversely, agglutination can also be used to identify new bacteria or cells with a specific antigen by exposing them to serum containing known agglutinins. [3]
Often expressed in cm/s. This value is inversely related to the total cross-sectional area of the blood vessel and also differs per cross-section, because in normal condition the blood flow has laminar characteristics. For this reason, the blood flow velocity is the fastest in the middle of the vessel and slowest at the vessel wall.
Erythrocyte aggregation is the reversible clumping of red blood cells (RBCs) under low shear forces or at stasis. Stacked red blood cells flow across drying slide. Erythrocytes aggregate in a special way, forming rouleaux. Rouleaux are stacks of erythrocytes which form because of the unique discoid shape of the cells in vertebrate body. The ...
Symptoms of AIHA may be due to the underlying anemia; including shortness of breath or dyspnea, fatigue, headache, muscle weakness and pallor. [10] In cold agglutinin disease (cold antibody type), agglutination and impaired passage of red blood cells through capillaries in the extremities causes acrocyanosis and Raynaud phenomenon with a rare complication of gangrene [4]
Neutrophils extravasate from blood vessels to the site of tissue injury or infection during the innate immune response.. In immunology, leukocyte extravasation (also commonly known as leukocyte adhesion cascade or diapedesis – the passage of cells through the intact vessel wall) is the movement of leukocytes (white blood cells) out of the circulatory system (extravasation) and towards the ...