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2. GLP-1 receptor agonist - Wikipedia

   en.wikipedia.org/wiki/GLP-1_receptor_agonist

   As a result, different GLP-1 agonist drugs are modified in various ways to extend the half-life, resulting in drugs that can be dosed multiple times per day, daily, weekly, or less often. [29] Most synthetic GLP-1 agonists are delivered via subcutaneous injection, which is a barrier to their use and reason for discontinuation. [37]

3. Semaglutide Side Effects: Is It Safe? What You Need To Know - AOL

   www.aol.com/semaglutide-side-effects-safe-know...

   Semaglutide is in a class called glucagon-like peptide-1 (GLP-1) receptor agonists. It works by mimicking GLP-1, a hormone the intestines naturally make. GLP-1 plays a key role in stimulating ...

4. Largest-ever Ozempic and GLP-1 drug study finds they lower ...

   www.aol.com/finance/largest-ever-ozempic-glp-1...

   As the GLP-1 patients in Al-Aly’s study were all veterans, with full drug coverage, their retention rate was higher—roughly 70% after a year. How the study’s results will be interpreted or ...

5. GLP1 poly-agonist peptides - Wikipedia

   en.wikipedia.org/wiki/GLP1_poly-agonist_peptides

   Tirzepatide, a dual agonist of GLP-1 and GIP receptors, is approved for type 2 diabetes and obesity. With an average 20 percent weight loss at a high dosage, it appears to be more effective than GLP-1 mono agonists although there have been no head to head trials as of 2023. [1] [3]

6. Glucagon-like peptide-1 - Wikipedia

   en.wikipedia.org/wiki/Glucagon-like_peptide-1

   Glucagon-like peptide-1 receptor agonists gained approval as drugs to treat diabetes and obesity starting in the 2000s. Endogenous GLP-1 is rapidly degraded primarily by dipeptidyl peptidase-4 (DPP-4), as well as neutral endopeptidase 24.11 (NEP 24.11) and renal clearance, resulting in a half-life of approximately 2 minutes. Consequently, only ...

7. Ozempic shown to reduce drinking in first trial in alcohol ...

   www.aol.com/news/ozempic-shown-reduce-drinking...

   Semaglutide, sold by Novo Nordisk as Ozempic for type 2 diabetes and Wegovy for obesity, is part of a class of drugs known as GLP-1 receptor agonists, mimicking the hormone GLP-1 to reduce ...