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Clinical equipoise allows investigators to continue a trial until they have enough statistical evidence to convince other experts of the validity of their results, without a loss of ethical integrity on the part of the investigators. Equipoise is also an important consideration in the design of a trial from a patient’s perspective.
Bioethics is both a field of study and professional practice, interested in ethical issues related to health (primarily focused on the human, but also increasingly includes animal ethics), including those emerging from advances in biology, medicine, and technologies.
A 40-year experiment conducted by the U.S. Public Health Service withheld standard medical advice and treatment from a poor minority population with an easily treatable disease. The experiment targeted black male farmers who were told they needed to be treated for 'bad blood', [27] but who were, in fact, syphilitic. In addition to many ...
A randomized controlled trial can provide compelling evidence that the study treatment causes an effect on human health. [ 6 ] The terms "RCT" and "randomized trial" are sometimes used synonymously, but the latter term omits mention of controls and can therefore describe studies that compare multiple treatment groups with each other in the ...
Medical ethics is closely related to bioethics, but these are not identical concepts. Since the science of bioethics arose in an evolutionary way in the continuation of the development of medical ethics, it covers a wider range of issues. [16] Medical ethics is also related to the law. But ethics and law are not identical concepts.
Sometimes this is also referred to as argument-based medical ethics. [3] It is also the title of the book Evidence-Based Medical Ethics: Cases for Practice-Based Learning [4] by John E. Snyder and Candace C. Gauthier, published by Humana-Springer Press in 2008 (ISBN 978-1-60327-245-2). While seen as a promising new approach to bioethical ...
The protocol should address the ethical issues and indicate that it is in compliance with the Declaration (Article 14). Studies should be discontinued if the available information indicates that the original considerations are no longer satisfied (Article 17). Information regarding the study should be publicly available (Article 16).
The Cambridge Quarterly of Healthcare Ethics is a quarterly peer-reviewed academic journal in the field of bioethics.It was established in 1992 with the goal of exploring "the many implications of both the broader issues in healthcare and society and of organizational concerns arising in the institutions in which ethics committees are located."