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Bottle of ephedrine, an alkaloid found in ephedra. Ephedra is a medicinal preparation from the plant Ephedra sinica. [1] [a] Several additional species belonging to the genus Ephedra have traditionally been used for a variety of medicinal purposes, and are a possible candidate for the soma plant of Indo-Iranian religion. [3]
Ephedrine works by inducing the release of norepinephrine and hence indirectly activating the α-and β-adrenergic receptors. [11] Chemically, ephedrine is a substituted amphetamine and is the (1R,2S)-enantiomer of β-hydroxy-N-methylamphetamine. [14] Ephedrine was first isolated in 1885 and came into commercial use in 1926.
The Ephedra alkaloids, ephedrine and pseudoephedrine – constituents of E. sinica and other members of the genus – have sympathomimetic and decongestant qualities, [22] and have been used as dietary supplements, mainly for weight loss. [23] The drug ephedrine is used to prevent low blood pressure during spinal anesthesia. [22]
Ephedra viridis, known by the common names green Mormon tea, Brigham tea, green ephedra, and Indian tea, is a species of Ephedra.It is indigenous to the Western United States, where it is a member of varied scrub, woodland, desert, and open habitats.
Ephedra (US-specific page on ephedrine-containing dietary supplements, observed (negative) health effects of these, and corresponding regulatory actions toward them) List of herbs with known adverse effects
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The pure alkaloid ephedrine from the Ephedra herbs is popular for effective medicine for asthma, especially because it can be given by mouth unlike adrenaline. [ 8 ] Ephedrine products are banned in U.S.A since 1994 for causing various and serious adverse effects, such as headache, insomnia, stroke, arrhythmias , myocardial infarction ...