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Alkalihalobacillus clausii (synonym Bacillus clausii) is a rod-shaped, motile, and spore-forming bacterium that lives in the soil but is also a natural microbiota of the mammalian gastrointestinal tract. It is classified as probiotic microorganism that maintains a symbiotic relationship with the host organism. [1]
The safety of fecal microbiota spores (live) was evaluated in a randomized, double-blind, placebo-controlled clinical study and an open-label clinical study conducted in the US and Canada. [2] The participants who suffered from recurrent C. difficile infection were subjected to 48 to 96 hours post-antibacterial treatment and their symptoms were ...
Probiotics are live microorganisms promoted with claims that they provide health benefits when consumed, generally by improving or restoring the gut microbiota. [1] [2] Probiotics are considered generally safe to consume, but may cause bacteria-host interactions and unwanted side effects in rare cases.
B. subtilis CU1 (2 × 10 9 spores per day) was evaluated in a 16-week study (10 days administration of probiotic, followed by 18 days wash-out period per each month; repeated same procedure for total 4 months) to healthy subjects. B. subtilis CU1 was found to be safe and well tolerated in the subjects without any side effects. [76]
The spore coat, which acts like a sieve that excludes large toxic molecules like lysozyme, is resistant to many toxic molecules and may also contain enzymes that are involved in germination. In Bacillus subtilus endospores, the spore coat is estimated to contain more than 70 coat proteins, which are organized into an inner and an outer coat ...
Patrick Mahomes wasn't selected for the 2025 Pro Bowl but he wouldn't have participated in it even if he was chosen. Here's why.