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Amenamevir (trade name Amenalief) is an antiviral drug used for the treatment of shingles (herpes zoster). It acts as an inhibitor of the zoster virus's helicase–primase complex. [1] [2] Amenamevir was approved in Japan for the treatment of shingles in 2017. [3]
Shingles, also known as herpes zoster or zona, [6] is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [7] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1]
A 2024 study of over 200,000 older US adults found that the recombinant shingles vaccine was linked to a larger reduction in dementia compared to the live shingles vaccine. [56] Over a six-year follow-up, those who received the recombinant vaccine had a 17% increase in time without a dementia diagnosis compared to those who received the live ...
Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. [6] Other uses include, prevention of cytomegalovirus infections following transplant, and severe complications of Epstein–Barr virus infection.
A systematic review did not find any evidence of any benefit in preventing vision loss in eyes treated with triamcinolone acetonide over placebo, for patients with age-related macular degeneration. [18] Triamcinolone acetonide is also administered via intralesional injection in the treatment of hypertrophic and keloid scars. [19] [20]
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