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The pumping action of the heart generates pulsatile blood flow, which is conducted into the arteries, across the micro-circulation and eventually, back via the venous system to the heart. During each heartbeat, systemic arterial blood pressure varies between a maximum ( systolic ) and a minimum ( diastolic ) pressure. [ 33 ]
Pulse wave velocity (PWV) is the velocity at which the blood pressure pulse propagates through the circulatory system, usually an artery or a combined length of arteries. [1] PWV is used clinically as a measure of arterial stiffness and can be readily measured non-invasively in humans, with measurement of carotid to femoral PWV (cfPWV) being ...
The Windkessel effect buffers the pulsatile ejection of blood from the heart converting it into a more steady, even outflow. This function depends on the elasticity of the arteries and stiffened arteries require a greater amount of force to permit them to accommodate the volume of blood ejected from the heart (stroke volume).
The flow profiles was first derived by John R. Womersley (1907–1958) in his work with blood flow in arteries. [1] The cardiovascular system of chordate animals is a very good example where pulsatile flow is found, but pulsatile flow is also observed in engines and hydraulic systems, as a result of rotating mechanisms pumping the fluid.
In medicine, Allen's test or the Allen test is a medical sign used in physical examination of arterial blood flow to the hands. It was named for Edgar Van Nuys Allen , who described the original version of the test in 1942.
A variety of blood tests are available for analyzing cholesterol transport behavior, HDL, LDL, triglycerides, lipoprotein little a, homocysteine, C-reactive protein, blood sugar control: fasting, after eating or averages using glycated albumen or hemoglobin, myoglobin, creatine kinase, troponin, brain-type natriuretic peptide, etc. to assess the evolution of coronary artery disease and ...
Pulse pressure is calculated as the difference between the systolic blood pressure and the diastolic blood pressure. [3] [4]The systemic pulse pressure is approximately proportional to stroke volume, or the amount of blood ejected from the left ventricle during systole (pump action) and inversely proportional to the compliance (similar to elasticity) of the aorta.
The classic definition by MP Spencer and AB Denison of compliance is the change in arterial blood volume due to a given change in arterial blood pressure ().They wrote this in the "Handbook of Physiology" in 1963 in work entitled "Pulsatile Flow in the Vascular System".