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Genetic rescue is seen as a mitigation strategy designed to restore genetic diversity and reduce extinction risks in small, isolated and frequently inbred populations. [1] It is largely implemented through translocation, a type of demographic rescue and technical migration that adds individuals to a population to prevent its potential extinction.
Revive & Restore is a nonprofit wildlife conservation organization focused on use of biotechnology in conservation.Headquartered in Sausalito, California, the organization's mission is to enhance biodiversity through the genetic rescue of endangered and extinct species.
Synthetic rescue (or synthetic recovery or synthetic viability when a lethal phenotype is rescued [1] [2]) refers to a genetic interaction in which a cell that is nonviable, sensitive to a specific drug, or otherwise impaired due to the presence of a genetic mutation becomes viable when the original mutation is combined with a second mutation in a different gene. [1]
Animal welfare organizations are concerned with the health, safety and psychological wellness of individual animals. These organizations include animal rescue groups and wildlife rehabilitation centers, which care for animals in distress and sanctuaries, where animals are brought to live and be protected for the rest of their lives.
Population bottleneck followed by recovery or extinction. A population bottleneck or genetic bottleneck is a sharp reduction in the size of a population due to environmental events such as famines, earthquakes, floods, fires, disease, and droughts; or human activities such as genocide, speciocide, widespread violence or intentional culling.
Alipogene tiparvovec (Glybera): AAV-based treatment for lipoprotein lipase deficiency (no longer commercially available); Axicabtagene ciloleucel (Yescarta): treatment for large B-cell lymphoma [1]
Genetic Information Research Institute; Joint Genome Institute (U.S. Department of Energy) Salk Institute for Biological Studies; Illinois. Carl R. Woese Institute for Genomic Biology (University of Illinois, Urbana-Champaign) Maine. The Jackson Laboratory; Maryland. Howard Hughes Medical Institute; J. Craig Venter Institute; Kennedy Krieger ...
Trisomic rescue (also known as trisomy rescue or trisomy zygote rescue) is a genetic phenomenon in which a fertilized ovum containing three copies of a chromosome loses one of these chromosomes (anaphase lag) to form a diploid chromosome complement. [1] If both of the retained chromosomes come from the same parent, then uniparental disomy ...