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Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development.
Stimulate appetite, secretion of growth hormone from anterior pituitary gland. 31 Glucagon: GCG Peptide: pancreas: alpha cells of Islets of Langerhans: Glucagon receptor → cAMP: glycogenolysis and gluconeogenesis in liver, activates lipase enzyme in adipose tissue cells, increases blood glucose level, inhibits storage of triglyceride in liver: 32
The hypothalamic–pituitary–somatotropic axis (HPS axis), or hypothalamic–pituitary–somatic axis, also known as the hypothalamic–pituitary–growth axis, is a hypothalamic–pituitary axis which includes the secretion of growth hormone (GH; somatotropin) from the somatotropes of the pituitary gland into the circulation and the subsequent stimulation of insulin-like growth factor 1 ...
In children, HGH stimulates linear growth and protein synthesis. It also helps with the breakdown of lipids fat, says O’Sullivan. ... Growth hormone is administered as a daily or once-weekly ...
Estrogen and progesterone cause the secretion of high levels of prolactin from the anterior pituitary, [32] [33] which reach levels as high as 20 times greater than normal menstrual cycle levels. [31] IGF-1 and IGF-2 levels also increase dramatically during pregnancy, due to secretion of placental growth hormone (PGH). [34]
Somatotropic hormone or growth hormone (GH) is an anabolic hormone that stimulates the growth of all body tissues especially skeletal muscle and bone. It may act directly, or indirectly via insulin-like growth factors (IGFs). GH mobilizes fats, stimulates protein synthesis, and inhibits glucose uptake and metabolism.
If there is an excess of growth hormone, it is usually because of over-secretion of somatotrope cells in the anterior pituitary gland. A significant amount of excess somatotrope secretion before puberty or before the end of new bone tissue growth can lead to gigantism, a disease that causes excess growth of body (e.g. being over 7 ft. tall) and unusually long limbs.
Growth hormone (somatotropin) GH: Somatotrophs: Stimulates growth and cell reproduction Stimulates Insulin-like growth factor 1 release from liver: Thyroid-stimulating hormone (thyrotropin) TSH: Thyrotropes: Stimulates thyroxine (T4) and triiodothyronine (T3) synthesis and release from thyroid gland Stimulates iodine absorption by thyroid gland