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The SC protein scaffold stabilizes the physical pairing of homologous chromosomes by polymerizing between them during meiotic prophase. [2] During synapsis, autosomes are held together by the synaptonemal complex along their whole length, whereas for sex chromosomes, this only takes place at one end of each chromosome. [3]
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Cell division producing haploid gametes For the figure of speech, see Meiosis (figure of speech). For the process whereby cell nuclei divide to produce two copies of themselves, see Mitosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
Meiosis undergoes two divisions resulting in four haploid daughter cells. Homologous chromosomes are separated in the first division of meiosis, such that each daughter cell has one copy of each chromosome. These chromosomes have already been replicated and have two sister chromatids which are then separated during the second division of ...
The chromosomes become visible as thin threadlike structures known as leptonema under a light microscope. [ 1 ] : 27 [ 2 ] : 353 Each chromosome consists of two identical sister chromatids held together by cohesin proteins along the entire length, connected at the centromere region.
The grasshopper Melanoplus femur-rubrum was exposed to an acute dose of X-rays during each individual stage of meiosis, and chiasma frequency was measured. [23] Irradiation during the leptotene-zygotene stages of meiosis (that is, prior to the pachytene period in which crossover recombination occurs) was found to increase subsequent chiasma ...
In any case, the temporal order of replication along the length of each chromosome can be plotted in graphical form to produce a "replication timing profile". Figure 4 shows an example of such a profile across 70,000,000 base pairs of human Chromosome 2.
Each chromosome consists of two closely associated sister chromatids along their entire length. The chromosomes appear as distinct, well-defined threadlike structures under the microscope. [3] [4] Sex chromosomes, however, are not wholly identical, and only exchange information over a small region of homology called the pseudoautosomal region. [5]
In zygotene, the synaptonemal complex forms more extensively between the paired chromosomes. It zips the homologs together along their entire length, with the lateral elements of the complex associated with each chromosome and the central region holding them together. This allows intimate pairing and genetic recombination events. [3] [4]