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Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. [4] Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth.
The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. [ 4 ] [ 5 ] In humans, the oxytocin receptor is encoded by the OXTR gene [ 6 ] [ 7 ] which has been localized to human chromosome 3p25 .
Synthetic oxytocin, sold under the brand name Pitocin among others, is a medication made from the peptide oxytocin. [ 6 ] [ 7 ] As a medication, it is used to cause contraction of the uterus to start labor , increase the speed of labor , and to stop bleeding following delivery . [ 6 ]
The following is a list of hormones found in Homo sapiens.Spelling is not uniform for many hormones. For example, current North American and international usage uses [citation needed] estrogen and gonadotropin, while British usage retains the Greek digraph in oestrogen and favours the earlier spelling gonadotrophin.
Oxytocin Is Released. Oxytocin is another chemical in the feel good cocktail that orgasm produces and one that affects women more so than men—namely because “when female brains develop in ...
Oxytocin, an example of an oxytocin receptor agonist.. An oxytocin receptor agonist is a compound that acts as an agonist of the oxytocin receptor. [1] [2] Examples include peptide oxytocin receptor agonists like oxytocin (Pitocin, Syntocinon), carbetocin (Duratocin, Pabal), and demoxytocin (Sandopart) and small-molecule oxytocin receptor agonists like TC OT 39, WAY-267464, and LIT-001.
A peptidergic agent (or drug) is a chemical which functions to directly modulate the peptide systems in the body or brain. An example is opioidergics , which are neuropeptidergics . A cell-penetrating peptide is a peptide able to penetrate the cell membrane.
LIT-001 is a small-molecule oxytocin receptor agonist and vasopressin receptor mixed agonist and antagonist that was first described in the literature in 2018. [1] [2] [3] Along with TC OT 39 and WAY-267464, it is one of the first small-molecule oxytocin receptor agonists to have been developed.