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Vaping presents health risks that are definitionally higher than those of simple abstinence, as no independent health benefits have been reported, while nicotine and cannabis have well-established harms. This comparison is relevant because some never-smokers adopt e-cigarettes for these drugs.
Exposure to nicotine and its great risk of developing an addiction, are areas of significant concern. [ 7 ] Nicotine is a parasympathomimetic stimulant [ 8 ] that binds to and activates nicotinic acetylcholine receptors in the brain, [ 9 ] which subsequently causes the release of dopamine and other neurotransmitters , such as norepinephrine ...
Smoking most commonly leads to diseases affecting the heart and lungs and will commonly affect areas such as hands or feet. First signs of smoking-related health issues often show up as numbness in the extremities, with smoking being a major risk factor for heart attacks, chronic obstructive pulmonary disease (COPD), emphysema, and cancer, particularly lung cancer, cancers of the larynx and ...
Risks to the child later in life from nicotine exposure during pregnancy include type 2 diabetes, obesity, hypertension, neurobehavioral defects, respiratory dysfunction, and infertility. [32] Nicotine exposure during pregnancy can result in attention deficit hyperactivity disorder (ADHD) and learning disabilities in the child.
The consumption of tobacco products and its harmful effects affect both smokers and non-smokers, [9] and is a major risk factor for six of the eight leading causes of deaths in the world, including respiratory diseases, cardiovascular diseases, cerebrovascular diseases, periodontal diseases, teeth decay and loss, over 20 different types or subtypes of cancers, strokes, several debilitating ...
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
A relatively new nicotine product with a tobacco-free and smokeless design has drawn in a wave of new users in just the past year: oral nicotine pouches that sit at the gums and are nearly ...
Nicotine replacement therapy (NRT) is the general term for using products that contain nicotine but not tobacco to aid smoking cessation. These include nicotine lozenges, nicotine gum and inhalers, nicotine patches, and electronic cigarettes. In a review of 136 NRT-related Cochrane Tobacco Addiction Group studies, substantial evidence supported ...