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Calciphylaxis, also known as calcific uremic arteriolopathy (CUA) or “Grey Scale”, is a rare syndrome characterized by painful skin lesions.The pathogenesis of calciphylaxis is unclear but believed to involve calcification of the small blood vessels located within the fatty tissue and deeper layers of the skin, blood clots, and eventual death of skin cells due to lack of blood flow. [1]
Hives, or urticaria, is a form of skin rash with red, raised, itchy bumps. [1] They may also burn or sting. [2] Hives can appear anywhere on the surface of the skin. Whether the trigger is allergic or not, a complex release of inflammatory mediators, including histamine from cutaneous mast cells, results in fluid leakage from superficial blood ...
Drugs which affect smooth muscle contraction, such as doxazosin, nitroglycerine, nifedipine and phenoxybenzamine, may provide pain relief. Uterine fibroids can be treated with the same methods as sporadic uterine fibroids including anti-hormonal treatment, surgery, or embolisation. Substantially elevated risk of progression to or independent ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
It may consist of topical corticosteroids and oral antihistamines for cutaneous symptoms such as hives and itching. [6] Mild cutaneous reactions can be managed with antihistamines only. [6] However, antihistamines cannot antagonize activated histamine that has already been released from mast cells. [7]
Symptoms are thought to be the result of histamine being released by mast cells on the surface of the skin. Despite the lack of antigens , histamine causes the skin to swell in affected areas. If the membrane that surrounds the mast cells is too weak, it will easily and rapidly break down under physical pressure, which then causes an allergic ...
Abruptly stopping your medication can result in flu-like symptoms, such as nausea, headache, fatigue and other effects relating to antidepressant discontinuation syndrome.
Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] [10] It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and social phobia. [7] The antidepressant effects may take one to four weeks to occur. [7]