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  2. Proteus syndrome - Wikipedia

    en.wikipedia.org/wiki/Proteus_syndrome

    Proteus syndrome is a rare genetic disorder [1] that can cause tissue overgrowth involving all three embryonic lineages. Patients with Proteus syndrome tend to have an increased risk of embryonic tumor development. [2] The clinical symptoms and radiographic findings of Proteus syndrome are highly variable, as are its orthopedic manifestations ...

  3. Bannayan–Riley–Ruvalcaba syndrome - Wikipedia

    en.wikipedia.org/wiki/Bannayan–Riley...

    Bannayan–Riley–Ruvalcaba syndrome; Other names: BRRS: Autosomal dominant is the manner in which this condition is inherited: Specialty: Oncology, medical genetics Symptoms: Enlarged head [1] Causes: Mutations in the PTEN gene [2] Diagnostic method: Based on signs and symptoms [3] Treatment: Based on symptoms [3]

  4. Overgrowth syndrome - Wikipedia

    en.wikipedia.org/wiki/Overgrowth_syndrome

    Children with some overgrowth syndromes such as Klippel–Trénaunay syndrome can be readily detectable at birth. [3] In contrast, other overgrowth syndromes such as Proteus syndrome usually present in the postnatal period, characteristically between the second and third year of life. [2]

  5. Her 3-Year-Old Died of Invasive Strep A. Now She's Educating ...

    www.aol.com/lifestyle/her-3-old-died-invasive...

    Before her death, Maddie was an "extraordinary big sister” to her then-3-month-old sibling, too. Related: 5-Year-Old Dies After Being Misdiagnosed by Doctors Who Said She Had a Cold

  6. Mandy Sellars - Wikipedia

    en.wikipedia.org/wiki/Mandy_Sellars

    In 2006, some doctors diagnosed Sellars as having Proteus syndrome, a very rare condition thought to affect only 120 people worldwide, [1] but more recent diagnoses have focused on a PIK3CA gene mutation. Some reports still describe her condition as a rare form of Proteus syndrome, [2] but Sellars herself has disputed the diagnosis. [3]

  7. Proteus-like syndrome - Wikipedia

    en.wikipedia.org/wiki/Proteus-like_syndrome

    Proteus-like syndrome (PLS) is a condition similar to Proteus syndrome, but with an uncertain cause. [1] It's characterized by skeletal and hamartous overgrowth of multiple tissues, nevi in cerebriform connective tissue, blood vessel malformations and linear epidermal nevi. [2] [3]

  8. Elephantiasis - Wikipedia

    en.wikipedia.org/wiki/Elephantiasis

    Elephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling (). [1] [2] It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels (). [2]

  9. Joseph Merrick - Wikipedia

    en.wikipedia.org/wiki/Joseph_Merrick

    Merrick died in the hospital on 11 April 1890. Although the official cause of his death was asphyxia, Treves, who performed the postmortem, concluded that Merrick had died of a dislocated neck. The exact cause of Merrick's deformities is unclear, but in 1986 it was conjectured that he had Proteus syndrome. In a 2003 study, DNA tests on his hair ...