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  2. Lumbar anterior root stimulator - Wikipedia

    en.wikipedia.org/wiki/Lumbar_anterior_root...

    A model showing the lumbar spinal area and pelvis, with spondylosis of the lumbar spine. A lumbar anterior root stimulator is a type of neuroprosthesis used in patients with a spinal cord injury or to treat some forms of chronic spinal pain.

  3. Epigenetics of chronic pain - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_chronic_pain

    Chronic pain can have a variety of causes, but one potential cause is the production of a pain wind-up, which is an increase in pain intensity in response to persistent activation of pain signals. This persistent pain reduces the threshold to feel pain over time and amplifies the pain response at the site of injury and surrounding areas.

  4. Diffuse noxious inhibitory control - Wikipedia

    en.wikipedia.org/wiki/Diffuse_noxious_inhibitory...

    Noxious stimuli activate the endings of nociceptive C and A delta nerve fibers, which carry the signal to neurons in the dorsal horn of spinal cord. DNIC refers to the mechanism by which dorsal horn wide dynamic range neurons responsive to stimulation from one location of the body may be inhibited by noxious stimuli (such as heat, high pressure or electric stimulation) applied to another ...

  5. Spinal cord injury research - Wikipedia

    en.wikipedia.org/wiki/Spinal_cord_injury_research

    The theory behind the new spinal cord stimulator is that in certain cases of spinal cord injury the spinal nerves between the brain and the legs are still alive, but just dormant. [48] On 1 November 2018 a third distinct research team from the University of Lausanne published similar results with a similar stimulation technique in the journal ...

  6. Spinal cord injury - Wikipedia

    en.wikipedia.org/wiki/Spinal_cord_injury

    In Pakistan, spinal cord injury is more common in males (92.68%) as compared to females in the 20–30 years of age group with a median age of 40 years, although people from 12–70 years of age suffered from spinal cord injury [73] Rates of injury are at their lowest in children, at their highest in the late teens to early twenties, then get ...

  7. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    The gate control theory of pain asserts that non-painful input closes the nerve "gates" to painful input, which prevents pain sensation from traveling to the central nervous system. In the top panel, the nonnociceptive, large-diameter sensory fiber (orange) is more active than the nociceptive small-diameter fiber (blue), therefore the net input ...