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Radiation-induced lumbar plexopathy (RILP) or radiation-induced lumbosacral plexopathy (RILSP) is nerve damage in the pelvis and lower spine area caused by therapeutic radiation treatments. RILP is a rare side effect of external beam radiation therapy [ 1 ] [ 2 ] [ 3 ] and both interstitial and intracavity brachytherapy radiation implants.
Management of brachial or lumbosacral plexopathy depends on the underlying cause. No matter the cause of plexopathy, physical therapy and/or occupational therapy may promote recovery of strength and improve limb function. In the case of a mass lesion causing compression of the brachial or lumbosacral plexus, surgical decompression may be warranted.
[1] [2] Many affected people are cancer survivors who had treatment for cervical cancer or prostate cancer. It has also been termed pelvic radiation disease with radiation proctitis being one of its principal features [3] and radiation-induced lumbar plexopathy (RILP) being a rare consequence. [4]
Radiation-induced lumbar plexopathy - nerve damage in the pelvis and lower spine area occurring as a late side effect of external beam radiation therapy. Review of International Law and Politics - a peer-reviewed law journal; RILP (gene) - a gene in humans that encodes the rab-interacting lysosomal protein
Radiation hormesis; Radiation-induced cognitive decline; Radiation protection; Radiation protection of patients; Radiation therapy; Radiation-induced cancer; Radiation-induced lumbar plexopathy; Radiation-induced lung injury; Radiation-induced thyroiditis; Radioactivity in the life sciences; Radiobiology evidence for protons and HZE nuclei ...
In the PNS, injury to the plexus nerves presents as radiation-induced brachial plexopathy or radiation-induced lumbosacral plexopathy appearing up to 3 decades post treatment. [43] Myokymia (muscle cramping, spasms or twitching) may develop.
Radiation oncology, also called radiation therapy or therapeutic radiology, is a speciality of medicine that uses various forms of radiation to treat disease, especially various cancers. In contrast, diagnostic radiology employs X-rays and other modalities for diagnostic imaging .
"Early delayed radiation-induced myelopathy" can manifest from six weeks to six months after treatment; the usual symptom is a Lhermitte sign ("a brief, unpleasant sensation of numbness, tingling and often electric-like discharge going from the neck to the spine and extremities, triggered by neck flexion"), usually followed by improvement two ...